Abstract

Antimicrobials are defined as substances of natural, semi-synthetic or synthetic origin that inhibits the growth of microorganisms (Aboaba et al; 2011). Some microorganisms have developed resistance to pharmaceutical drugs. Medicinal plants have been used from time past to treat different kind of illness, hence, the need to study antimicrobial properties of ethanolic extract of Tetrapleura teraptera (Aidan). 100g of powdered Tetrapleura tetraptera leave sample was poured into a sterile airtight glass jar and 400ml of extract (ethanol) was added to it and the mixture was agitated vigorously. The prepared nutrient agar was heated for 15 minutes using the autoclave. The cooled nutrient agar was poured into series of petri plates. The zone of inhibition shown by various isolates was determined using Agar well diffusion method. The antimicrobial analysis of the leaves extract of Tetrapleura tetraptera with nutrient agar medium showed that all the microorganism are resistant to the extract while Escherichia coli and Proteus species, were susceptible to the antimicrobial effect of Tetrapleura tetraptera leaves extract. Klebsiella pneumoniae has the highest susceptibility to the plant extract antimicrobial property. The extract have potent invivo antibacterial activities against Klebsiella pneumonia, Proteus species E. coli, and Staphylococcus aureus thus a veritable source of new antimicrobial agent.